Half-human and half-yokai, one-eyed Kitaro (Wentz Eiji) lives with his eyeball father and his bickering friends, Nezumi Otoko (Oizumi Yo) and Neko Musume (Tanaka Lena), in Gegege Forest where he dedicates his time to maintaining peace between humans and yokai.

But when a magical ball of power ends up in the wrong hands, Kitaro must recover it or both worlds could fall into grave danger.